Niveau de consommation en acides gras polyinsaturés de la femme allaitante en France : étude de consommation INCA2 et évolution du contenu en acides gras essentiels du lait
Auteurs : C. Billeaud, C. Boué-Vaysse, L Couëdelo, P. Steenhout, J. Jaeger, C. Cruz-Hernandez, L. Ameye, J. Rigo, J-C. Picaud, E. Saliba, N.P. Hays and F. Destaillats
OCL 2018, 25(3), D304
Infants were randomized to receive HM supplemented with either a new HM fortifier (nHMF ; n = 26) containing 12.5 g medium-chain FA (MCFA), 958 mg linoleic acid (LA), 417 mg α-linolenic acid (ALA), and 157 mg docosahexaenoic acid (DHA) per 100 g of powder (in compliance with the latest guidelines) or a fat-free HMF (cHMF ; n = 21).
Plasma phospholipid (PL) and triacylglycerol (TAG), and red blood cell phosphatidylcholine (RBC-PC) and phosphatidylethanolamine (RBC-PE) FA profiles were assessed before and after 21 days of feeding. In the nHMF group, significantly increased levels of n-9 monounsaturated fatty acids were observed, formed most likely by elongation and desaturation of dietary saturated fatty acids present in HM.
ALA fortification increased ALA assimilation into plasma TAG.
Similarly, DHA fortification enriched the DHA content in RBC-PE, which, in this compartment, was not associated with lower arachidonic acid levels as observed in plasma TAG and phospholipids. RBC-PE, a reliable indicator of FA metabolism and accretion, was the most sensitive compartment in this study.