Lipid-protein interactions from oilseeds :

impact on their digestibility
and interest in the prevention of sarcopenia associated with aging

At the end of 2021, ITERG's Health Nutrition & Lipid Biochemistry Team started a new research project in collaboration with Stéphane Walrand from the Food, Muscle Health and Sarcopenia Team (ASMS), one of the 5 research teams constituting the Human Nutrition Unit, a Joint Research Unit (UMR) 1019 between INRAE and the University of Clermont Auvergne (UCA). https://www6.clermont.inrae.fr/unh/Recherche/Equipes/ASMS

Entitled ProLiDiA , it will be conducted by Lina Toutirais under a CIFRE agreement with the ANRT (2021-2024).

This thesis project plans to exploit the nutritional potential of different plant protein matrices (concentrates, isolates) derived from oilseeds by studying the interest of a combined supply of amino acids and essential fatty acids on the muscular health of the elderly subject.
Among the various targeted objectives, the effects of these different protein matrices and their formulation with lipids of interest on the digestibility and metabolic efficiency of the protein and lipid nutrients in these formulas will be evaluated.

In line with the national roadmap "Innovative products for a safe, healthy and sustainable food supply of the 34 plans of the new industrial France" and the challenges of the plant protein plan, a priority of the agricultural section of the "France Relance" plan, this work will generally contribute to enriching the knowledge of the partners on the nutritional value of new protein sources and the complementarity of protein and lipid intakes within the framework of the prevention of muscle, adipocyte and hepatic lipid and protein metabolism disorders during aging.

The results acquired during this thesis will be published in peer-reviewed scientific journals, presented at national and international conferences, and communicated to the general public and to the sectors of interest.